Seeking CBD Oil's Fullest Potential: The Entourage Effect

October 7, 2019

Discerning CBD shoppers come to us because we produce high-quality, full-spectrum CBD oil. Sometimes a customer asks us: "What exactly does a full-spectrum CBD oil do for me?"

Our answer? Well, if there is one leading reason why we believe in using the whole plant to produce CBD oil, it can be expressed in two words:

Entourage effect.

It's a fascinating topic to explore. Let's take a little time and look.

What Is the Entourage Effect? Finding CBD's Fullest Potential.

We believe that the fullest expression of CBD can be found in the whole plant. Think of the saying "greater than the sum of its parts." Isolated Cannabis sativa compounds might work well for certain purposes, but when multiple, rich compounds are together, they harmonize. Each one supports and brings out the best of the rest.

This is why we focus on creating an outstanding blend of compounds — including some of the hemp plant's most sought-after and beautifully fragrant terpenes.

The composition of terpenes in whole-plant CBD oil plays a significant role in how we experience cannabinoids such as CBD. This interplay, the entourage effect, differs according to the unique makeup of the CBD oil you select.

Let's Talk Terpenes. Which Ones Are in MtivaCBD's Entourage?

In MtivaCBD;s full-spectrum, hemp-derived oil, CBD plays the starring role. But it's not alone. Today, we'd like to introduce you the terpenes in our CBD's entourage. They all have a special synergy with CBD and with each other. Meet:  


This is a favorite and familiar compound. Where have you met beta-caryophyllene before? In a rich, red India pale ale. In a Mediterranean-style dinner that features basil, rosemary, or oregano fresh from your garden. In a warm chai tea, spiced with black pepper, cinnamon, and cloves.

It's also in hemp. It's long been sough after for folk medicine, praised for its pain-soothing effects. It was among the first cannabis compounds proven to bind to the endocannabinoid receptors in our bodies.


Found in bay leaves, parsley, lemongrass, and mangoes, myrcene promotes a gentle relaxation.

In 2011, Dr. Ethan Russo found what researchers called "phytocannabinoid-terpenoid synergy" — effects from the blend of plant-derived cannabinoids and terpenes — in clinical studies later published by the British Journal of Pharmacology. The detailed publication explained that myrcene engages cannabinoids to produce phytocannabinoid-terpenoid entourage effects that result in therapeutic benefits. For instance, their clinical studies examined myrcene as it combined with CBD. The combination correlated to a reduction in swelling and pain. The research also indicated myrcene's significant potential in cancer research.


As the name suggests, this terpene is connected with the bracing fragrance of pine needles. It also appears in sage and dill. How might it work synergistically with other hemp-derived compounds?

Ethan Russo cites work suggesting that alpha pinene could help conserve acetylcholine molecules. These have been implicated in our ability to form memories.


Does the word remind you of lemons? It should. In fact, limonene is a terpene that exists in any citrus fruit rind. So it, too, is another familiar player in the entourage. It's also a pretty popular substance among people with unsettled stomachs!

Limonene may collaborate with CBD, and with other terpenes, including caryophyllene. It also lets cells accept compounds more easily, helping the body's assimilation of CBD.

All of these terpenes have long been associated with a synergy with cannabinoids in the hemp plant. Plant breeders have long thought, for example, that the CBD in traditional cannabis can work together with THC, and tone down its strongest effects.  

Fascinating Potential

For all these reasons and more, full-spectrum CBD oil, including major terpenes, has fascinating potential in an overall strategy for well-being. At Mtiva, the more we learn about the entourage effect, the more excited we are to share our explorations with our clientele.

Terpenes are aromatic and complex compounds that come straight from the glands of the hemp plant. Whole-plant CBD oil can offer a spectrum of terpenes, while the CO2 extraction method works to preserve their natural traits and distinctive fragrances.

CBD connoisseurs often have preferences for particular hemp-derived terpenes, with their signature effects. And this is why the CBD oil we make is a full-spectrum blend. At the end of the day it will always be the whole plant, not any one compound, that does its best job as nature intended.

Maybe you had no idea, but we have all have experienced terpenes from plants throughout our lives. They give an orange its citrus scent. They give pine trees their unique and attractive aroma. They are chemicals that determine how things smell. And as we learn about the ways in which they each interact with other compounds in plants, we see CBD's potential in a new and exciting light.  

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